Improved efficacy and tolerability of retinoic acid in acne vulgaris: a new topical formulation with cyclodextrin complex psi

Anadolu R., Sen T., Tarimci N., Birol A., Erdem C.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, cilt.18, sa.4, ss.416-421, 2004 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 4
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1111/j.1468-3083.2004.00929.x
  • Dergi Adı: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.416-421
  • Anahtar Kelimeler: retinoic acid, cyclodextrin, acne vulgaris, TRETINOIN GEL 0.025-PERCENT, PERCUTANEOUS-ABSORPTION, 0.1-PERCENT, DRUGS, DELIVERY, SKIN
  • Ankara Üniversitesi Adresli: Hayır

Özet

Objectives Retinoic acid (RA) has long been used, both topically and systemically, for disorders of keratinization, acne and related disorders. In the present study, the efficacy and tolerability of topical RA prepared as a cyclodextrin beta complex (beta-CD) is investigated in 66 acne vulgaris patients.