An intensive approach to the treatment of disseminated BCG infection in a SCID patient
BONE MARROW TRANSPLANTATION, cilt.30, sa.1, ss.45-47, 2002 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 30 Sayı: 1
- Basım Tarihi: 2002
- Doi Numarası: 10.1038/sj.bmt.1703578
- Dergi Adı: BONE MARROW TRANSPLANTATION
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.45-47
- Anahtar Kelimeler: allogeneic BMT, SCID, disseminated BCG disease, SEVERE COMBINED IMMUNODEFICIENCY, TRANSPLANTATION, MARROW
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ankara Üniversitesi Adresli: Evet
Özet
There is an appreciable mortality associated with BMT in patients with SCID and advanced BCG infection. We present a girl with T-B+ SCID complicated by spina ventosa and disseminated BCG osteitis after receiving a fully matched sibling marrow transplant. Considerable progression characterised by two clinical activations and multiple pleural and perivertebral abscess formations occurred with conventional anti-mycobacterial chemotherapy. She finally recovered with full immune reconstitution after BMT and intensive treatment comprising five conventional and alternative agents that she received for 36 months. No side-effects and/or complications have been seen other than hearing loss.