Graphene Quantum Dot-poly(L-lysine)-gold Nanoparticles Nanocomposite for Electrochemical Determination of Dopamine and Serotonin

Simsek N., AYDOĞDU TIĞ G.

ELECTROANALYSIS, cilt.34, sa.1, ss.61-73, 2022 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1002/elan.202100442
  • Dergi Adı: ELECTROANALYSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Applied Science & Technology Source, BIOSIS, Chemical Abstracts Core, Chimica, Communication Abstracts, Metadex, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.61-73
  • Anahtar Kelimeler: Dopamine, serotonin, graphene quantum dots, AuNPs, voltammetric determination, POLY-L-LYSINE, METAL-ORGANIC FRAMEWORKS, WALLED CARBON NANOTUBES, ASCORBIC-ACID, VOLTAMMETRIC DETERMINATION, SENSITIVE DETECTION, SENSOR, ELECTRODE, COMPOSITE, BIOSENSOR
  • Ankara Üniversitesi Adresli: Evet

Özet

A nanocomposite consists of AuNPs, GQD, and poly(L-lysine) was prepared for highly sensitive electrochemical determination of dopamine (DA) and serotonin (5-HT) neurotransmitters which are of vital importance in neurological disorders. The P(L-Lys) GQD was successfully obtained a one-step co-electrodeposition of GQD and L-Lys on the PGE. The electrochemical behaviors of DA and 5-HT were analyzed via DPV and CV. LOD values for DA and 5-HT were calculated as 0.03 mu M and 0.017 mu M, respectively. Also, the DA and 5-HT contents were determined at the PGE/AuNPs/P(L-Lys)-GQD in fetal bovine serum samples and pharmaceutical formulations, and high recovery values were obtained.