Fanconi anemia with the presentation of abdominal rhabdomyosarcoma followed by acute myeloid leukemia

Gözdaşoǧlu S., Yavuz G., Gökçora H., Uysal Z., Babacan E., Bökesoy I., ...Daha Fazla

Turkish Journal of Cancer, cilt.37, sa.4, ss.154-157, 2007 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 4
  • Basım Tarihi: 2007
  • Dergi Adı: Turkish Journal of Cancer
  • Derginin Tarandığı İndeksler: Scopus, Academic Search Premier
  • Sayfa Sayıları: ss.154-157
  • Anahtar Kelimeler: Acute myeloid leukemia, Fanconi anemia, Rhabdomyosarcoma
  • Ankara Üniversitesi Adresli: Evet

Özet

The objective of this study is to present an unusual case of Fanconi anemia (FA) with an initial presentation of abdominal rhabdomyosarcoma followed by acute myeloid leukemia (AML). Although epithelial cancers are more often seen in FA patients, rarities such as osteosarcomas, soft-tissue tumors and brain cancers have been reported in the literature. The present case was treated with VACA treatment (vincristine, actinomycin D, cyclophosphamide and adriamycin) and radiotherapy following initial assessment through surgery and histopathological evaluation. A second malignancy AML developed 17 months after completion of initial treatment and the patient died at 2 months remission and 6 months survival following the diagnosis of AML.