Effect of depth of invasion on lymph node metastasis in early stage

ÖZDEN N. S., Aydinli Y., Babayev N., ÖZDEMİR A., KAYA B.

TURKISH JOURNAL OF PLASTIC SURGERY, cilt.28, sa.1, ss.29-32, 2020 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.4103/tjps.tjps_8_19
  • Dergi Adı: TURKISH JOURNAL OF PLASTIC SURGERY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, Directory of Open Access Journals
  • Sayfa Sayıları: ss.29-32
  • Anahtar Kelimeler: Elective lymph node dissection, lip cancer, lymph node metastasis, squamous cell carcinoma, SQUAMOUS-CELL CARCINOMA, PROGNOSTIC-FACTORS, OCCULT METASTASIS, NECK DISSECTION, ORAL-CAVITY, CANCER, HEAD, MANAGEMENT, PREDICTOR, THICKNESS
  • Ankara Üniversitesi Adresli: Evet

Özet

Introduction: Lip cancer is the most common type of cancer in the oral cavity. It occurs in the lower lip at a rate of 90%-95%, and among lower lip tumors, squamous cell carcinoma (SCC) is the most common type. Objective: In this study, we investigated the influence of the depth of invasion on the decision for an elective lymph node dissection in cases with early-stage (T1-T2 N0 M0) SCC of the lower lip. Methods: Thirty-two patients that were surgically treated were retrospectively reviewed. Results: Three patients had metastatic lymph node, and their mean depth of invasion was 10.60 mm. Lymph node metastasis significantly increased in tumors with a depth of invasion larger than 5 mm (P = 0.033). Conclusion: The rate of cervical lymph node metastasis increases as the depth of invasion increases.