Akademik Veri Yönetim Sistemi
European Respiratory Society Annual Congress, Amsterdam, Hollanda, 27 Eylül - 01 Ekim 2025, cilt.66, ss.5727, (Özet Bildiri)
Introduction-purpose: This study aims to compare FEV₁ values and z-scores in the assessment of the degree of obstruction according to GOLD criteria.
Method: This study was designed as a retrospective cohort and conducted on patients diagnosed with COPD who visited our clinic throughout 2024 and had available pulmonary function test(PFT)data.The z-scores of the patients were calculated based on Global Lung Initiative 2012 standards according to their GOLD stages and PFT results. Patients' demographic data were recorded through face-to-face interviews and the hospital information system. Based on their FEV₁ Z-scores, patients were classified as healthy,mild,moderate,or severe.
Results: There was no significant relationship between the Z-score and demographic variables. When the degree of airway obstruction determined by the Z-score was compared with GOLD A,B,and E groups,no statistically significant difference was observed. However,73.9% of patients classified as healthy according to the Z-score were found to be in GOLD Group E. It was determined that 63.7% of GOLD Group E patients were classified as healthy or in the mild obstruction group according to the Z-score.Patients with moderate Z-scores were more evenly distributed among GOLD A,B,and E groups. Among patients with severe Z-scores,50% were in GOLD Group E,while the remaining 50% were equally distributed between GOLD A and B.
Discussion: The Z-score may underestimate airflow limitation in severe COPD, misclassifying high-risk patients as healthy. This study shows that it does not fully align with GOLD classification and may be insufficient for clinical decisions, highlighting the need for a more comprehensive assessment.