JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, cilt.133, sa.6, ss.1651-1671, 2014 (SCI-Expanded)
Background: Alterations of immune homeostasis in the gut can result in development of inflammatory bowel disease (IBD). Recently, Mendelian forms of IBD have been discovered, as exemplified by deficiency of IL-10 or its receptor subunits. In addition, other types of primary immunodeficiency disorders might be associated with intestinal inflammation as one of their leading clinical presentations.