Synthesis and antimicrobial activity of some new 3-substituted benzyl-5-(4-chloro-2-piperidin-1yl-thiazole-5-yl-methylene)-thiazolidine-2, 4-dione derivatives

Ceylan Ünlüsoy M., BOZDAĞ DÜNDAR O., ALTANLAR N., Ertan R.

Turkish Journal of Chemistry, vol.30, no.3, pp.355-360, 2006 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 3
  • Publication Date: 2006
  • Journal Name: Turkish Journal of Chemistry
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.355-360
  • Keywords: Antimicrobial activities, Thiazole derivatives, Thiazolidine-2,4-diones
  • Ankara University Affiliated: Yes

Abstract

A new series of thiazolyl thiazolidine-2,4-dione (Va-f) were synthesized and their structures were elucidated by IR, 1H-NMR, mass spectra and elementary analysis. The synthesized compounds were tested for their antimicrobial activities against Candida albicans, Staphylococcus aureus, Bacillus subtilis and Escherichia coli. Compounds Va-b, Vd-f showed high activity against Escherichia coli comparable to ampicillin. © TÜBİTAK.