A live birth after transfer of a day 2 embryo derived from frozen-thawed zygotes that had undergone polar body biopsy: a case report

Ozmen B., Schoepper B., Schultz-Mosgau A., Youssry M., Diedrich K., Al-Hasani S.

Fertility and Sterility, vol.90, no.4, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 90 Issue: 4
  • Publication Date: 2008
  • Doi Number: 10.1016/j.fertnstert.2007.09.037
  • Journal Name: Fertility and Sterility
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Polar body biopsy, pregnancy, cryopreservation, freezing, thawing, HUMAN OOCYTES, BLASTOMERE BIOPSY, ZONA-PELLUCIDA, CRYOPRESERVATION, VITRIFICATION, SURVIVAL, PREGNANCY, STAGE, BLASTOCYST
  • Ankara University Affiliated: No

Abstract

Objective: To present a live birth after freezing and thawing of biopsied oocytes. Design: Case report. Setting: Artificial reproduction unit of a university hospital. Patient(s): A primary infertile couple with asthenoteratozoospermia and repeated failures of intracytoplasmic sperm injection (ICSI). Intervention(s): Screening of aneuploidy during the fourth ICSI cycle with polar body biopsy (PB) for repeated failures of artificial reproductive techniques and a transfer of a cryopreserved day 2 embryo derived from cryopreserved zygotes with slow-rate freezing after PB. Main Outcomes Measure(s): Live birth, viability, and survival. Result(s): A successful pregnancy and a live birth were presented after a transfer of day 2 embryos derived from oocytes that underwent PB and subsequent cryopreservation. Conclusion(s): Pregnancy can be obtained subsequent to cryopreservation and thawing after PB. © 2008 American Society for Reproductive Medicine.