Blood viscosity in patients with diffuse large B cell non-Hodgkin's lymphoma

Utkan G., Tek I., Kocer M., Muallaoglu S., Durnali A., Arslan U., ...More

Experimental Oncology, vol.28, no.4, pp.326-327, 2006 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 4
  • Publication Date: 2006
  • Journal Name: Experimental Oncology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.326-327
  • Keywords: Blood viscosity, Non-Hodgkin's lymphoma
  • Ankara University Affiliated: Yes

Abstract

The aim of the study was to evaluate blood viscosity as possible marker of disease progression in patients with newly diagnosed non-Hodgkin's lymphoma (NHL). Methods: The viscosity of blood samples from 20 patients with newly diagnosed aggressive NHL (stage I, n = 7; stage II, n = 4; stage III, n = 7; stage IV, n = 2) was analyzed using Brookfield DV-II + (USA) machine. Results: Blood viscosity in NHL patients (median: 5.5 ± 1.46 miliPascal) inversely correlated with lactatdehydrogenase (LDH) level, international prognostic index (IPI) score, and stage (p = 0.02, r= -0.51; p = 0.03, r= -0.63; and p = 0.04, r= -0.45, respectively) and positively correlated with hemoglobin level (p = 0.02, r = 0.65)). Conclusion: According to our data, blood viscosity may be considered as a follow up marker in NHL patients along with LDH level or sedimentation rate. Copyright © Experimental Oncology, 2006.