4,5-dianilinophtalimide protects neuroendocrine cells against serum deprivation-induced stress and apoptosis

Ergin V., ERDOĞAN M., KARASU Ç., Menevse A.

NEUROENDOCRINOLOGY LETTERS, vol.34, no.5, pp.359-365, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 5
  • Publication Date: 2013
  • Journal Name: NEUROENDOCRINOLOGY LETTERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.359-365
  • Keywords: DAPH, serum deprivation, apoptosis, cellular stress, PC12, OXIDATIVE STRESS, HEAT-SHOCK, C-JUN, DEATH, KINASE, P38, INHIBITION, ACTIVATION, NEURONS, DISEASE
  • Ankara University Affiliated: No

Abstract

OBJECTIVE: The aim of this study was to reveal the effects of 4,5-dianilinophthalimide (DAPH), which inhibits amyloid beta fibrillization, against serum deprivation (SD)-induced apoptosis and the possible mechanisms in differentiated PC12 neuron cells.