Early initiation of extracorporeal photochemotherapy increases response for chronic graft versus host disease following steroid failure

Gunduz M., Atilla E., Atilla P. A., Topcuoglu P., Ilhan O.

TRANSFUSION CLINIQUE ET BIOLOGIQUE, vol.26, no.1, pp.32-37, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.1016/j.tracli.2018.03.005
  • Journal Name: TRANSFUSION CLINIQUE ET BIOLOGIQUE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.32-37
  • Keywords: Graft versus host disease, Extracorporeal photochemotherapy, CONSENSUS DEVELOPMENT PROJECT, CLINICAL-TRIALS, CHRONIC GVHD, PHOTOPHERESIS, SURVIVAL, THERAPY, EFFICACY, CRITERIA, UPDATE, RISK
  • Ankara University Affiliated: Yes

Abstract

Objectives. - Chronic graft versus host disease (GVHD) is one of the major obstacles to achieve success in allogeneic hematopoietic stem cell transplantation (allo-HSCT). Extracorporeal photochemotherapy (ECP) has been demonstrated to be an effective modality for the treatment of GVHD in previous studies but they vary in terms of initiation and duration. Our aim is to demonstrate the characteristics of our patients who received ECP for chronic GVHD to clarify the best treatment scheme.