Relationship between plasma leptin, insulin and tumor necrosis factor alpha in obese children


AYCAN Z., BERBEROĞLU M., Ocal G., EVLİYAOĞLU S. O., Adiyaman P., Deda G., ...Daha Fazla

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.18, sa.3, ss.275-284, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 3
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1515/jpem.2005.18.3.275
  • Dergi Adı: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.275-284
  • Anahtar Kelimeler: leptin, tumor necrosis factor alpha, insulin, obesity, TYROSINE-KINASE-ACTIVITY, SUBCUTANEOUS ADIPOSE-TISSUE, BODY-MASS INDEX, PROMOTER POLYMORPHISM, OB PROTEIN, RESISTANCE, GENE, SENSITIVITY, EXPRESSION, RECEPTOR
  • Ankara Üniversitesi Adresli: Evet

Özet

Objectives: 1. To evaluate the relationship between plasma leptin and TNF alpha concentrations in obese children and to assess the differences between hyperinsulinemic and normoinsulinemic groups. 2. To evaluate the relationship between plasma leptin and insulin levels in obese children. 3. To investigate the TNF alpha G308A mutation in obese children.