Lipid peroxidation level and antioxidant enzyme activities in septicemic calves

MERAL Ö., ERCAN N., Fidanci U. R.

ANKARA UNIVERSITESI VETERINER FAKULTESI DERGISI, cilt.64, sa.3, ss.161-164, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 64 Sayı: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1501/vetfak_0000002793
  • Dergi Adı: ANKARA UNIVERSITESI VETERINER FAKULTESI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.161-164
  • Anahtar Kelimeler: Glutathione peroxidase, neonatal septicemia, oxidative stress, superoxide dismutase, OXIDATIVE STRESS, MECHANISM, OXIDANTS, BLOOD
  • Ankara Üniversitesi Adresli: Evet

Özet

In recent years, studies showed that there is a close relationship between oxidative stress and pathogenesis of the disease. The aim of the study is to determine the serum malondialdehyde (MDA) levels for lipid peroxidation status and serum glutathione peroxidase (GPx), superoxide dismutase (SOD), total bilirubin and albumin levels for antioxidant activities to find out the possible relationship between oxidative stress and septicemia in calves. The materials of this study are 40 septicemic and 13 healthy calves. No significant differences were observed for serum MDA and albumin levels between septicemic and healthy groups (p>0.05). Septicemic calves had significantly higher levels of GPx, SOD and total bilirubin as compared to the controls (p<0.001). The results obtained from this study suggest that septicemia in calves induced changes of antioxidant enzymes activity. The data obtained from this study indicates that oxidative stress might play important roles in the pathogenesis of septicemia in calves.