Is carnosine effective to alleviate lung injury: a systematic review

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Yalaza M., Akin I., Altiner S., ARIBAL AYRAL P., YAZIHAN N.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.47, sa.1, ss.1-7, 2022 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 47 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1515/tjb-2021-0073
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, Food Science & Technology Abstracts, Directory of Open Access Journals
  • Sayfa Sayıları: ss.1-7
  • Anahtar Kelimeler: carnosine, lung, lung injury, respiratory diseases, systematic review, NITRIC-OXIDE, FLUID, PATHOGENESIS, GLUTATHIONE
  • Ankara Üniversitesi Adresli: Evet

Özet

Objectives: Lung injury is one of the most important risk factor for morbidity and mortality, especially in older people. There are several reasons causing acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) such as pneumonia, sepsis, viruses, oxidants, and trauma. Evidence has shown that carnosine has many properties, such as suppressing hydroxyl, superoxide, and peroxyl radicals, inhibiting peroxidation, membrane protection and wound healing. We aimed to analyze the effects of carnosine on lung injury in this systematic review.