Is carnosine effective to alleviate lung injury: a systematic review

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Yalaza M., Akin I., Altiner S., ARIBAL AYRAL P., YAZIHAN N.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.47, no.1, pp.1-7, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Review
  • Volume: 47 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.1515/tjb-2021-0073
  • Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, Food Science & Technology Abstracts, Directory of Open Access Journals
  • Page Numbers: pp.1-7
  • Keywords: carnosine, lung, lung injury, respiratory diseases, systematic review, NITRIC-OXIDE, FLUID, PATHOGENESIS, GLUTATHIONE
  • Ankara University Affiliated: Yes

Abstract

Objectives: Lung injury is one of the most important risk factor for morbidity and mortality, especially in older people. There are several reasons causing acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) such as pneumonia, sepsis, viruses, oxidants, and trauma. Evidence has shown that carnosine has many properties, such as suppressing hydroxyl, superoxide, and peroxyl radicals, inhibiting peroxidation, membrane protection and wound healing. We aimed to analyze the effects of carnosine on lung injury in this systematic review.