A Retrospective Evaluation on Demographic, Phenomenological, and Comorbidity Features of Pediatric Obsessive-Compulsive Disorder

Efe A., AÇIKEL S. B., Uygun S. D., Canl M., Temelturk R. D., Gurel Y., ...Daha Fazla

JOURNAL OF NERVOUS AND MENTAL DISEASE, cilt.210, sa.1, ss.6-25, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 210 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1097/nmd.0000000000001402
  • Dergi Adı: JOURNAL OF NERVOUS AND MENTAL DISEASE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, Academic Search Premier, ATLA Religion Database, BIOSIS, CAB Abstracts, Child Development & Adolescent Studies, CINAHL, Educational research abstracts (ERA), EMBASE, MEDLINE, MLA - Modern Language Association Database, Psycinfo, Violence & Abuse Abstracts
  • Sayfa Sayıları: ss.6-25
  • Anahtar Kelimeler: Obsessive-compulsive disorder, sociodemographic, symptom dimension, phenotype, child psychiatry, ATTENTION-DEFICIT/HYPERACTIVITY DISORDER, CLINICAL-FEATURES, RISK-FACTORS, BIPOLAR COMORBIDITY, SPECTRUM DISORDERS, SYMPTOM DIMENSIONS, TREATMENT DURATION, GENDER-DIFFERENCES, ANXIETY DISORDERS, REFERRED CHILDREN
  • Ankara Üniversitesi Adresli: Evet

Özet

The impacts of sex, age of onset, phenotype, and comorbidity on clinical features were explored in a large clinical sample with pediatric obsessive-compulsive disorder (p-OCD) (n = 457), along with concomitant specific features in the framework of different symptom dimensions/phenotypes, by a retrospective cross-sectional evaluation design. The most prevalent phenotype was obsession/checking (almost half), and the clinical features belonging to different phenotypes varied among sexes, age of onset, severity, and comorbidities. The contamination and aggressive obsessions, along with the compulsions such as cleaning and repeating routine activities, were the most prevalent symptoms, which were prevalently accompanied by generalized anxiety disorder, attention deficit hyperactivity disorder, and depression. Females with OCD were likely prone to exhibit comorbid internalizing disorders, whereas males were prone to externalizing. This recent study on a large Turkish clinical sample of p-OCD followed up within 5 years, highlighting separate evidence on subtyping of p-OCD in phenotype and comorbidity frame.