Concurrent peste des petits ruminants virus and pestivirus infection in stillborn twin lambs

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Kul O., Kabakci N., ÖZKUL A., Kalender H., Atmaca H. T.

VETERINARY PATHOLOGY, cilt.45, sa.2, ss.191-196, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 2
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1354/vp.45-2-191
  • Dergi Adı: VETERINARY PATHOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.191-196
  • Anahtar Kelimeler: border disease, congenital infection, immunohistochemistry, lambs, peste des petits ruminants, pestivirus, polymerase chain reaction, BORDER DISEASE VIRUS, VIRAL-DIARRHEA-VIRUS, PATHOLOGICAL FINDINGS, CONGENITAL INFECTION, NEWBORN LAMBS, SPINAL-CORD, SHEEP, TURKEY, BOVINE, GOATS
  • Ankara Üniversitesi Adresli: Evet

Özet

Concurrent infection with peste des petits ruminants virus (PPRV) and pestivirus was diagnosed in stillborn twin lambs. With the flock history, the findings of epidermal syncytial cells and necrotizing bronchitis/bronchiolitis prompted testing for PPRV infection, and PPRV antigen was detected by immunohistochemistry (IHC) in the skin, lungs, kidneys, rumen, and thymus. Macroscopic anomalies that were typical of border disease included scoliosis, brachygnathism, prognathism, arthrogryposis, hydranencephaly, cerebellar hypoplasia, and hairy fleece; pestiviral antigen was detected by IHC in the brain, liver, lungs, and kidneys. Tissues from both lambs were positive by reverse transcriptase-polymerase chain reaction (RT-PCR) for PPRV and pestivirus. To the authors' knowledge, PPR has not been reported previously as a congenital infection or in combination with pestiviral infection.