Experimental study of the effect of preoperative 5-fluorouracil on the integrity of colonic anastomoses

KUZU M. A., Koksoy C., Kale T., Demirpence E., Renda N.

BRITISH JOURNAL OF SURGERY, cilt.85, sa.2, ss.236-239, 1998 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 85 Sayı: 2
  • Basım Tarihi: 1998
  • Doi Numarası: 10.1046/j.1365-2168.1998.02876.x
  • Dergi Adı: BRITISH JOURNAL OF SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.236-239
  • Ankara Üniversitesi Adresli: Hayır

Özet

Background Despite curative resection for colorectal cancer, many patients develop recurrence at the primary site or distant organs, These patients are candidates for (neo)-adjuvant chemotherapy. Very little is known about the effect of preoperative 5-fluorouracil (FU) on the healing of colonic anastomoses. The aim of this study was to assess this in a rat model.