Bilateral coronary artery dilatation and supravalvular pulmonary stenosis in a child with Noonan syndrome

UÇAR T., Atalay S., Tekin M., Tutar E.

PEDIATRIC CARDIOLOGY, vol.26, no.6, pp.848-850, 2005 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 6
  • Publication Date: 2005
  • Doi Number: 10.1007/s00246-005-0935-2
  • Journal Name: PEDIATRIC CARDIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.848-850
  • Keywords: Noonan syndrome, coronary artery dilatation, supravalvular pulmonary stenosis
  • Ankara University Affiliated: No

Abstract

Noonan syndrome is the second most frequent congenital malformation syndrome, after Down syndrome, associated with cardiovascular abnormalities. The most prevalent cardiovascular abnormalities in Noonan syndrome are pulmonary stenosis and hypertrophic cardiomyopathy. We report the case of a 12-year-old girl with Noonan syndrome who had multiple cardiovascular abnormalities, including extensive bilateral coronary artery dilatation, valvular and supravalvular pulmonary stenosis, atrial septal defect, and mitral valve prolapse. Both coronary artery dilatation and supravalvular pulmonary stenosis, although rarely reported, are abnormalities of the cardiovascular system that may occur in Noonan syndrome.