Synthesis and antimicrobial testing of some flavonylsulfonamide derivatives

Kilcigil G., Dundar O., Ertan R., Altanlar N.

TURKISH JOURNAL OF CHEMISTRY, vol.27, no.4, pp.461-465, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 4
  • Publication Date: 2003
  • Journal Name: TURKISH JOURNAL OF CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.461-465
  • Keywords: flavonylsulfonamides, synthesis, antimicrobial, FLAVONE DERIVATIVES, HYPOGLYCEMIC ACTIVITY
  • Ankara University Affiliated: Yes

Abstract

Six new 4-amino-N-heteroaryl,N-[(2-phenyl-4H-1-benzopyran-4-oxo-6-yl)metil]benzensulfonamide derivatives, (3a-3f) were prepared by reacting 6-bromomethylflavone with the corresponding sulfonamide derivatives and their antimicrobial activities against Escherichia coli were evaluated. All of the compounds exhibited better activity (except compound 3c) than the corresponding sulfonamide derivatives.