Investigation of respiratory syncytial virus (RSV) neutralization antibody prevalence in adults Eriskinlerde respiratory syncytial virus (RSV) notralizan antikor prevalansinin arastirilmasi

Ozsan M., ÖZKUL A., CENGİZ A.

Ondokuz Mayis Universitesi Tip Dergisi, cilt.16, sa.1, ss.43-46, 1999 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 1
  • Basım Tarihi: 1999
  • Dergi Adı: Ondokuz Mayis Universitesi Tip Dergisi
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.43-46
  • Anahtar Kelimeler: Neutralization peroxidase linked antibody assay (NPLA), Respiratory syncytial virus
  • Ankara Üniversitesi Adresli: Evet

Özet

Respiratory syncytial virus (RSV) causes respiratory system infections in humans and has a worldwide distribution. These infections can be severe and rarely fatal especially in infants. The aim of this study is to investigate the prevalence of neutralizing antibody levels against RSV among adults. 134 sera that were sent to Ankara University Faculty of Medicine, Department of Microbiology and Clinical Microbiology serology laboratory for various serological tests were studied. We investigated antibodies against RSV with neutralization peroxidase linked antibody assay (NPLA). Out of 134 serum samples, neutralizing antibodies were found in 97 (72.4%). The most abundant neutralizing titer was calculated as to be 1/80 in 33 of 97 seropositive individuals. These seropositivity rates reflect the importance of RSV in respiratory system infections. RSV should be in mind in order not to delay the treatment of respiratory system infections that might be to viruses.