Laser flare photometry and its use in uveitis

Tugal-Tutkun I., Yalçındağ N., Herbort C. P.

Expert Review of Ophthalmology, vol.7, no.5, pp.449-457, 2012 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 5
  • Publication Date: 2012
  • Doi Number: 10.1586/eop.12.47
  • Journal Name: Expert Review of Ophthalmology
  • Journal Indexes: Scopus
  • Page Numbers: pp.449-457
  • Keywords: anterior chamber cells, aqueous flare, blood–aqueous barrier, intraocular inflammation, laser flare photometry, laser flare-cell photometry, uveitis
  • Ankara University Affiliated: Yes

Abstract

Intraocular inflammation causes disruption of the blood–ocular barriers and entry of proteins and inflammatory cells into the aqueous humor. Slit-lamp examination allows only a subjective and arbitrary grading of cells and flare (protein) in the anterior chamber. Laser flare photometry is the only objective and quantitative method to reliably measure intraocular inflammation. Flare measurements by laser flare photometry enables exact monitoring of both acute and chronic uveitic entities. Recent studies showing the predictive value of flare levels for disease outcomes have revolutinized therapeutic approach in uveitis, placing flare to the center of inflammatory parameters to be targeted for better outcomes. © 2012, Expert Reviews Ltd. All rights reserved.