New pathway in rheumatic mitral valve disease: cytochrome P450 and glutathione S transferase isozyme expression

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Simsek E., Simsek G., Soyal M. F. T., Kaygin P., Duzgun A. C., YILMAZ SARIALTIN S., ...Daha Fazla

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.45, sa.6, ss.869-875, 2020 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 6
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1515/tjb-2019-0302
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.869-875
  • Anahtar Kelimeler: Rheumatic mitral valve disease, Ischemic mitral valve insufficency, GST isozyme expression, Cytochrome P450, Glutathione S-transferase, OXIDATIVE STRESS, C-11 ACETATE, METABOLISM, EFFICIENCY, ENZYMES, PROTEIN, TUMOR, CYP
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: Cytochrome P450 (CYP)1A1, glutathione S-transferase pi (GSTP1) and omega (GSTO1) isozymes were evaluated and compared in patients with the diagnosis of rheumatic mitral valve disease and ischemic mitral valve insufficiency to find out the relationship of the oxidative stress with rheumatic mitral valve disease.