New pathway in rheumatic mitral valve disease: cytochrome P450 and glutathione S transferase isozyme expression

---

Simsek E., Simsek G., Soyal M. F. T., Kaygin P., Duzgun A. C., YILMAZ SARIALTIN S., ...More

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.45, no.6, pp.869-875, 2020 (SCI-Expanded, Scopus, TRDizin)

• Publication Type: Article / Article
• Volume: 45 Issue: 6
• Publication Date: 2020
• Doi Number: 10.1515/tjb-2019-0302
• Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, TR DİZİN (ULAKBİM)
• Page Numbers: pp.869-875
• Keywords: Rheumatic mitral valve disease, Ischemic mitral valve insufficency, GST isozyme expression, Cytochrome P450, Glutathione S-transferase, OXIDATIVE STRESS, C-11 ACETATE, METABOLISM, EFFICIENCY, ENZYMES, PROTEIN, TUMOR, CYP
• Open Archive Collection: AVESIS Open Access Collection
• Ankara University Affiliated: Yes

Abstract

Objective: Cytochrome P450 (CYP)1A1, glutathione S-transferase pi (GSTP1) and omega (GSTO1) isozymes were evaluated and compared in patients with the diagnosis of rheumatic mitral valve disease and ischemic mitral valve insufficiency to find out the relationship of the oxidative stress with rheumatic mitral valve disease.