Apoptotic and necrotic death mechanisms are concomitantly activated in the same cell after cerebral ischemia

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Unal-Cevik I., Kilinc M., Can A., Gursoy-Ozdemir Y., Dalkara T.

STROKE, vol.35, no.9, pp.2189-2194, 2004 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 35 Issue: 9
  • Publication Date: 2004
  • Doi Number: 10.1161/01.str.0000136149.81831.c5
  • Journal Name: STROKE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2189-2194
  • Keywords: apoptosis, caspases, cathepsins, cerebral ischemia, focal, necrosis, SITU DNA FRAGMENTATION, NITRIC-OXIDE, NEURONAL APOPTOSIS, CASPASE ACTIVATION, ARTERY OCCLUSION, FOCAL ISCHEMIA, DISTINCT, BRAIN, DEPRIVATION, CATHEPSIN
  • Open Archive Collection: AVESIS Open Access Collection
  • Ankara University Affiliated: Yes

Abstract

Background and Purpose - Both necrotic and apoptotic cell death mechanisms are activated after cerebral ischemia. However, whether they are concomitantly active in the same cell or in discrete cell populations is not known.