Photodynamic Therapy Based on Graphene and MXene in Cancer Theranostics

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Gazzi A., Fusco L., Khan A., Bedognetti D., Zavan B., Vitale F., ...Daha Fazla

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, cilt.7, 2019 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 7
  • Basım Tarihi: 2019
  • Doi Numarası: 10.3389/fbioe.2019.00295
  • Dergi Adı: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: photodynamic therapy, theranostics, graphene, MXene, nanomedicine, NANO-GRAPHENE, QUANTUM DOTS, CHEMICAL FUNCTIONALIZATION, CARBIDE MXENE, TI3C2 MXENE, OXIDE, DELIVERY, NANOSHEETS, PHOTOSENSITIZERS, FLUORESCENCE
  • Ankara Üniversitesi Adresli: Evet

Özet

Cancer is one of the leading causes of death in the world. Therefore, the development of new advanced and targeted strategies in cancer research for early diagnosis and treatment has become essential to improve diagnosis outcomes and reduce therapy side effects. Graphene and more recently, MXene, are the main representatives of the family of two-dimensional (2D) materials and are widely studied as multimodal nanoplatforms for cancer diagnostics and treatment, in particular leveraging their potentialities as photodynamic therapeutic agents. Indeed, due to their irreplaceable physicochemical properties, they are virtuous allies for photodynamic therapy (PDT) in combination with bioimaging, photothermal therapy, as well as drug and gene delivery. In this review, the rapidly progressing literature related to the use of these promising 2D materials for cancer theranostics is described in detail, highlighting all their possible future advances in PDT.