Complete ciliary aplasia; a rare form of primary ciliary dyskinesia

Ergün P., Deniz P. P., Erdoǧan Y., Turay Ü. Y., Biber Ç., Çiftçi B., ...Daha Fazla

Turk Toraks Dergisi, cilt.11, sa.3, ss.121-123, 2010 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Sayı: 3
  • Basım Tarihi: 2010
  • Doi Numarası: 10.5152/ttd.2010.17
  • Dergi Adı: Turk Toraks Dergisi
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.121-123
  • Anahtar Kelimeler: Bronchiectasis, Ciliary aplasia, Dyskinesia
  • Ankara Üniversitesi Adresli: Evet

Özet

This report describes the ultrastructural alterations observed in the bronchial mucosa of a 29-year old male patient suffering from chronic upper and lower respiratory tract infections since his childhood and operated due to bronchiectasis and sinusitis. Electron microscopic evaluation of the bronchial biopsy specimens revealed ciliated cells appeared to be replaced by columnar cells lacking cilia and basal bodies, and bearing on their surface cilium-like projections without any internal axonemal structure. These ultrastructural features are consistent with complete ciliary aplasia which is a rare form of primary ciliary dyskinesia.