The ultrastructure of the parasite and the mucus cell relationship and endogenous stages of Cryptosporidium muris in the stomach of laboratory mice

Aydin Y.

TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES, vol.23, no.2, pp.117-125, 1999 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 2
  • Publication Date: 1999
  • Journal Name: TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.117-125
  • Keywords: laboratory mice, stomach, Cryptosporidium muris, ultrastructure, ABOMASAL CRYPTOSPORIDIOSIS, STRAIN RN-66, ANIMALS, INFECTIVITY, PENETRATION, RHOPTRIES, CATTLE
  • Ankara University Affiliated: No

Abstract

The ultrastructure of endogenous stages of Cryptosporidium muris in the stomach of laboratory mice was studied by transmission electron microscopy. Electron microscopy showed the various developmental stages as free in the gastric gland lumina and attached to the mucus cells. The changes in organelle composition and structure of various stages from the sporozoite to young trophozoites and matured oocysts were demonstrated in detail. Two types of the meront were discriminated. The finding of a microgamete on the parasitophorous vacuolar membrane surrounded a macrogamont was interesting for the stage of fertilization in C. muris. Types 1 and 2 wall-forming bodies were present in fertilized macrogamete or zygote. During sequential development of the endogenous stages, the zygote was separated: from the attachment organelle by the clefts, the sporogony process simultaneously appeared when the wall formation progressed, and the sporoblasts were enveloped by budding from the sporont. As a result, thick and thin walled oocysts were found in the parasitophorous vacuole.