Vascular endothelial growth factor, endostatin levels and clinical features among patients with ulcerative colitis and irritable bowel syndrome and among healthy controls: a cross-sectional analytical study

Aksoy E. K., Cetinkaya H., SAVAŞ B., ENSARİ A., Torgutalpv M., Efe C.

SAO PAULO MEDICAL JOURNAL, vol.136, no.6, pp.543-550, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 136 Issue: 6
  • Publication Date: 2018
  • Doi Number: 10.1590/1516-3180.2018.0274161118
  • Journal Name: SAO PAULO MEDICAL JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.543-550
  • Keywords: Colitis, ulcerative, Vascular endothelial growth factors, Endostatins, SERUM-LEVELS, CROHNS-DISEASE, VEGF, ANGIOGENESIS
  • Ankara University Affiliated: Yes

Abstract

BACKGROUND: Increased angiogenetic activity in inflammatory bowel disease (IBD) has been shown in previous studies. The aim of this study was to evaluate the relationship of serum vascular endothelial growth factor (VEGF) and endostatin levels with clinical features and mucosal expression in patients with ulcerative colitis (UC).