Efficacy of aripiprazole augmentation in treatment resistant obsessive compulsive disorder: A case report

Tuzer V., Bulut S. D., Ak E., BAŞTUĞ G., Goka E.

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, cilt.19, 2009 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19
  • Basım Tarihi: 2009
  • Dergi Adı: KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), TR DİZİN (ULAKBİM)
  • Anahtar Kelimeler: Aripiprazole, obsessive-compulsive disorder, augmentation, treatment resistant, DOPAMINE, SYMPTOMS
  • Ankara Üniversitesi Adresli: Hayır

Özet

Although serotonin re-uptake inhibitors are the most effective and established treatments for obsessive-compulsive disorder, 40 to 60% of the patients do not respond adequately to the medication. The use of new generation antipsychotics in treatment resistant obsessive-compulsive disorder or in cases where augmentation treatment is indicated have been reported to be successful. However there is not much data on use of one of the medications in this group, aripiprazole. This study presents the improvement observed in a case of treatment resistant obsessive-compulsive disorder where aripiprazole was used for augmentation treatment and the discussion on probable mechanisms of action.