Evaluation of brain natriuretic peptide levels in hyperthyroidism and hypothyroidism

Ertugrul D. T., Gursoy A., ŞAHİN M., Unal A. D., Pamuk B., Berberoglu Z., ...Daha Fazla

JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION, cilt.100, sa.4, ss.401-405, 2008 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 100 Sayı: 4
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/s0027-9684(15)31272-4
  • Dergi Adı: JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.401-405
  • Anahtar Kelimeler: thyroid, heart, ENDOGENOUS SUBCLINICAL HYPERTHYROIDISM, THYROID-FUNCTION STATES, HEART-FAILURE, A-TYPE, ATRIAL, GENE, DYSFUNCTION, EXPRESSION, RELEASE, BNP
  • Ankara Üniversitesi Adresli: Hayır

Özet

Background: Brain natriuretic peptide (BNP) is secreted from the ventricular myocardium in response to volume expansion and pressure overload. Serum BNP levels are also affected by thyroid function status, which was mostly related to a direct stimulatory effect of thyroid hormones on the secretion of BNP. Although the diagnostic value of BNP in heart failure is undisputed, its value in the presence of the thyroid dysfunction has been recently questioned. The aim of this study was to evaluate the influence of thyroid dysfunction on BNP levels.