Defibrillation Testing and Early Neurologic Outcome

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Karaoguz R., Altln T., Atbasoglu E. C., TOGAY IŞIKAY C., Gueraslan B., Akyuerek O., ...Daha Fazla

INTERNATIONAL HEART JOURNAL, cilt.49, sa.5, ss.553-563, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 5
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1536/ihj.49.553
  • Dergi Adı: INTERNATIONAL HEART JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.553-563
  • Anahtar Kelimeler: Implantable cardioverter defibrillator, Neuron specific enolase, Neuronal injury, Cognitive function, IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR, NEURON-SPECIFIC ENOLASE, VENTRICULAR-FIBRILLATION, NEUROBIOCHEMICAL MARKERS, CARDIAC-ARREST, HEART-FAILURE, DYSFUNCTION, RELEASE, SURGERY, DAMAGE
  • Ankara Üniversitesi Adresli: Evet

Özet

During implantable cardioverter-defibrillator (ICD) implantation, ventricular defibrillation testing (DFT) is considered a standard procedure. This procedure often requires multiple ventricular fibrillation (VF) inductions. These repeated short episodes of circulatory arrest with global cerebral ischemia may cause neurological damage. In the present study, patients undergoing initial ICD implantation and limited induction of VF for defibrillation safety margin testing were evaluated for pre- and postoperative cognitive and neurologic functions. In addition, the serum neuron specific enolase (NSE) level, which is a biochemical marker of cerebral injury, was evaluated.