NSAIDs: Behind the mechanisms of action

Tulunay F.

FUNCTIONAL NEUROLOGY, vol.15, no.3, pp.202-207, 2000 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 3
  • Publication Date: 2000
  • Journal Name: FUNCTIONAL NEUROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.202-207
  • Keywords: COX, migraine, NSAID, prostaglandin, EXPRESSION, SYNTHASE
  • Ankara University Affiliated: No

Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) are a heterogeneous group of compounds. These heterogeneous agents have a similar therapeutic action for the treatment of pain. fever and inflammation. The major mechanism of action of NSAIDs is the inhibition of cyclooxygenase (COX). the enzyme catalysing the synthesis of prostaglandins (PGs).