NSAIDs: Behind the mechanisms of action

Tulunay F.

FUNCTIONAL NEUROLOGY, cilt.15, sa.3, ss.202-207, 2000 (SCI-Expanded, Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 3
  • Basım Tarihi: 2000
  • Dergi Adı: FUNCTIONAL NEUROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.202-207
  • Anahtar Kelimeler: COX, migraine, NSAID, prostaglandin, EXPRESSION, SYNTHASE
  • Ankara Üniversitesi Adresli: Hayır

Özet

Non-steroidal anti-inflammatory drugs (NSAIDs) are a heterogeneous group of compounds. These heterogeneous agents have a similar therapeutic action for the treatment of pain. fever and inflammation. The major mechanism of action of NSAIDs is the inhibition of cyclooxygenase (COX). the enzyme catalysing the synthesis of prostaglandins (PGs).