Effectiveness of Antibiotics Given to Asymptomatic Men for an Increased Prostate Specific Antigen

Baltaci S., SÜER E., Haliloglu A. H., GÖKCE M. İ., ELHAN A. H., Beduek Y.

JOURNAL OF UROLOGY, cilt.181, sa.1, ss.128-132, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 181 Sayı: 1
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.juro.2008.09.020
  • Dergi Adı: JOURNAL OF UROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.128-132
  • Anahtar Kelimeler: prostate-specific antigen, anti-bacterial agents, prostatic neoplasms, ANTIBACTERIAL THERAPY, PSA LEVELS, SERUM PSA, INFLAMMATION, CANCER, LEVEL, NG/ML
  • Ankara Üniversitesi Adresli: Evet

Özet

Purpose: Although there is controversy surrounding this subject, some urologists in daily practice often prescribe antibiotics before biopsy to men with a newly increased prostate specific antigen. We evaluated the effects of antibiotics on serum total prostate specific antigen, free prostate specific antigen, percent free prostate specific antigen and prostate specific antigen density in men with prostate specific antigen between 4 and 10 ng/ml and normal digital rectal examination. We also investigated the incidence of prostate cancer after antibiotic treatment by performing prostate biopsies in all patients regardless of posttreatment prostate specific antigen.