Optimization of Immobilized Aldose Reductase Isolated from Bovine Liver

Nasliyan M. V., BEREKETOĞLU NERGİS S., YILDIRIM Ö.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.16, sa.2, ss.206-210, 2019 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 2
  • Basım Tarihi: 2019
  • Doi Numarası: 10.4274/tjps.81894
  • Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.206-210
  • Anahtar Kelimeler: Aldose reductase, isolation, immobilization, HYDROLYSIS, GELATIN, LIPASE
  • Ankara Üniversitesi Adresli: Evet

Özet

Objectives: Isolation of enzymes and experiments on them require great effort and cost and are time-consuming. Therefore, it is important to extend the usability of the enzymes by immobilizing them. In this study our purpose was to immobilize the enzyme aldose reductase (AR) and to optimize the experimental conditions of the immobilized AR and compare them to those of free AR.