Optimization of Immobilized Aldose Reductase Isolated from Bovine Liver

Nasliyan M. V., BEREKETOĞLU NERGİS S., YILDIRIM Ö.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, vol.16, no.2, pp.206-210, 2019 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.4274/tjps.81894
  • Journal Name: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.206-210
  • Keywords: Aldose reductase, isolation, immobilization, HYDROLYSIS, GELATIN, LIPASE
  • Ankara University Affiliated: Yes

Abstract

Objectives: Isolation of enzymes and experiments on them require great effort and cost and are time-consuming. Therefore, it is important to extend the usability of the enzymes by immobilizing them. In this study our purpose was to immobilize the enzyme aldose reductase (AR) and to optimize the experimental conditions of the immobilized AR and compare them to those of free AR.