Antioxidant potential, oxidation resistance and MDA levels of cancerous and noncancerous human colorectal tissues

Durak I., Kocaoglu H., Kacmaz M., Cimen M., Buyukkocak S., ÖZTÜRK H. S.

CANCER RESEARCH THERAPY & CONTROL, cilt.5, sa.4, ss.295-299, 1998 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 5 Sayı: 4
  • Basım Tarihi: 1998
  • Dergi Adı: CANCER RESEARCH THERAPY & CONTROL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.295-299
  • Anahtar Kelimeler: antioxidant potential, oxidation resistance, malondialdehyde, colon cancer, GLUTATHIONE S-TRANSFERASE, TUMOR PROMOTION, SUPEROXIDE-DISMUTASE, VITAMIN-E, LIPID-PEROXIDATION, FREE-RADICALS, INHIBITION, EXPRESSION, SYSTEMS
  • Ankara Üniversitesi Adresli: Evet

Özet

Antioxidant potential (AOP), oxidation resistance (OR) and malondialdehyde (MDA) levels of cancerous and non-cancerous adjacent colorectal tissues from 13 patients with colorectal adenocancer were measured to investigate oxidant/antioxidant status of the tissues. AOP of the cancerous tissues was found to be significantly lower than that of non-cancerous ones. However, OR and MDA levels of cancerous tissues were not different from those of non-cancerous ones. In the correlation analysis carried out between analysis parameters, significant differences were found in the cancerous tissues.