Highly selective electrochemical determination of forever chemicals (PFAS) via MIP sensors: A review on current trends
Trends in Environmental Analytical Chemistry, cilt.51, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 51
- Basım Tarihi: 2026
- Doi Numarası: 10.1016/j.teac.2026.e00314
- Dergi Adı: Trends in Environmental Analytical Chemistry
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Chemical Abstracts Core
- Anahtar Kelimeler: Electrochemical sensors, Environmental analysis, Molecularly imprinted polymers (MIP), PFAS
- Ankara Üniversitesi Adresli: Evet
Özet
Per- and polyfluoroalkyl substances (PFAS), widely known as “forever chemicals,” have emerged as a critical environmental and public health concern due to their exceptional chemical stability, persistence, and bioaccumulation potential. Their widespread use in industrial and consumer applications has led to global contamination of water, soil, and food systems, necessitating highly sensitive and selective analytical methods for their detection at ultra-trace levels. Although conventional techniques offer high accuracy and reliability, their limitations in terms of cost, complexity, and on-site applicability have driven the search for alternative sensing platforms. In this context, electrochemical sensors integrated with molecularly imprinted polymers (MIPs) have gained significant attention as promising tools for PFAS detection. MIPs provide artificial recognition sites with high selectivity via template-specific cavities, enabling the detection of electrochemically inactive PFAS via indirect sensing strategies. This review provides a comprehensive overview of current trends in MIP-based electrochemical sensors for PFAS analysis, covering fundamental design principles, polymerization techniques, sensing mechanisms, and recent technological advancements. Additionally, key challenges, including selectivity among structurally similar PFAS, sensor stability, and scalability, are critically discussed. Future perspectives highlight the need for multiplex detection systems, improved material design, and the development of portable, real-time monitoring platforms. Overall, electrochemical MIP sensors represent a powerful and evolving alternative to conventional methods, with strong potential for environmental monitoring and regulatory applications.