Prevalence of Factor V 1691 G-A (Leiden) and prothrombin G20210A polymorphisms and the risk of venous thrombosis among cancer patients

Eroglu A., Ulu A., Cam R., Kurtman C., Akar N.

JOURNAL OF THROMBOSIS AND THROMBOLYSIS, cilt.23, sa.1, ss.31-34, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 1
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1007/s11239-006-9001-z
  • Dergi Adı: JOURNAL OF THROMBOSIS AND THROMBOLYSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.31-34
  • Anahtar Kelimeler: cancer, thromboembolism, FVL, PT G20210A, ONCOLOGY PATIENTS, BREAST-CANCER, MUTATION, THROMBOEMBOLISM, RESISTANCE, INSIGHTS, COMMON, GENE
  • Ankara Üniversitesi Adresli: Evet

Özet

Aims Cancer patients have an increased risk for thromboembolism (TE). Factor V 1691 G-A(Leiden) (FVL) and prothrombin (PT) G20210A mutation are common inherited risk factor for TE. The aim of the study is to evaluate the prevalence of FVL and PT G20210A polymorphism in cancer patients with and without TE as compared to patients with TE without malignancy and healthy control.