Prevalence of Factor V 1691 G-A (Leiden) and prothrombin G20210A polymorphisms and the risk of venous thrombosis among cancer patients

Eroglu A., Ulu A., Cam R., Kurtman C., Akar N.

JOURNAL OF THROMBOSIS AND THROMBOLYSIS, vol.23, no.1, pp.31-34, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 1
  • Publication Date: 2007
  • Doi Number: 10.1007/s11239-006-9001-z
  • Journal Name: JOURNAL OF THROMBOSIS AND THROMBOLYSIS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.31-34
  • Keywords: cancer, thromboembolism, FVL, PT G20210A, ONCOLOGY PATIENTS, BREAST-CANCER, MUTATION, THROMBOEMBOLISM, RESISTANCE, INSIGHTS, COMMON, GENE
  • Ankara University Affiliated: Yes

Abstract

Aims Cancer patients have an increased risk for thromboembolism (TE). Factor V 1691 G-A(Leiden) (FVL) and prothrombin (PT) G20210A mutation are common inherited risk factor for TE. The aim of the study is to evaluate the prevalence of FVL and PT G20210A polymorphism in cancer patients with and without TE as compared to patients with TE without malignancy and healthy control.