Ratio-spectra zero-crossing derivative spectrophotometric determination of certain drugs in two-component mixtures

Erk N.

ANALYTICAL LETTERS, cilt.32, sa.7, ss.1371-1388, 1999 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 7
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1080/00032719908542904
  • Dergi Adı: ANALYTICAL LETTERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1371-1388
  • Anahtar Kelimeler: two component mixtures, simultaneous determination, ratio-spectra zero-crossing derivative spectrophotometric, pharmaceutical formulations, PERFORMANCE LIQUID-CHROMATOGRAPHY, UV SPECTROPHOTOMETRY, HYDROCHLOROTHIAZIDE, TABLETS, HYDROCHLORIDE, FORMULATIONS, COMBINATION
  • Ankara Üniversitesi Adresli: Evet

Özet

Two two-component mixtures have been assayed using both Vierordt's method and ratio-spectra zero-crossing derivative spectrophotometric methods. Such mixtures are hydrochlorothiazide-spironolactone and hydrochlorothiazide-ramipril. These selected applications illustrate the relative ease and simplicity offered by ratio - spectra zero-crossing derivative spectrophotometry for the assay of two component mixtures with spectral interferences from matrix formulations.