Effect of the gonadotropin-releasing hormone antagonist ganirelix on cyclic adenosine monophosphate accumulation of human granulosa-lutein cells

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Demirel L., Weiss J., Polack S., Unlu C., Diedrich K., Ortmann O.

FERTILITY AND STERILITY, vol.74, no.5, pp.1001-1007, 2000 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 74 Issue: 5
• Publication Date: 2000
• Doi Number: 10.1016/s0015-0282(00)01552-1
• Journal Name: FERTILITY AND STERILITY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1001-1007
• Keywords: ganirelix, cAMP, hCG, granulosa cells, cumulus cells, MESSENGER-RIBONUCLEIC-ACID, IN-VITRO FERTILIZATION, OVARIAN FOLLICLE, PROGESTERONE SECRETION, HYPOPHYSECTOMIZED RATS, INHIBITORY ACTIONS, GNRH RECEPTOR, AGONIST, STEROIDOGENESIS, EXPRESSION
• Ankara University Affiliated: No

Abstract

Objective: To evaluate whether the GnRH antagonist ganirelix exerts an effect on cyclic adenosine monophosphate (cAMP) production of human granulosa-lutein (GL) cells in vitro.