Procedural Characteristics, Safety, and Follow-up of Modified Right-Sided Approach for Cardioneuroablation


CANDEMİR B., Baskovski E., Beton O., Shanableh N., AKBULUT KOYUNCU İ. M., KOZLUCA V., ...Daha Fazla

ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.26, sa.8, ss.629-636, 2022 (SCI-Expanded, Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 8
  • Basım Tarihi: 2022
  • Doi Numarası: 10.5152/anatoljcardiol.2022.217
  • Dergi Adı: ANATOLIAN JOURNAL OF CARDIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.629-636
  • Anahtar Kelimeler: Cardioneuroablation, intermittent AV block, radiofrequency ablation, vasovagal syncope, GANGLIONATED PLEXI ABLATION, SINUS, INDUCIBILITY, INNERVATION, SYNCOPE, ATRIUM
  • Ankara Üniversitesi Adresli: Evet

Özet

Background: Cardioneuroablation is one of the emerging therapies in vasovagal syncope. In this study, we present a simple method of cardioneuroablation performed via a right-sided approach, targeting anterior-right and right-inferior ganglionated plexi, along with procedural and follow-up data. Methods: Patients who had underwent cardioneuroablation between March 2018 and September 2019 with vasovagal syncope in 2 clinics were enrolled in the study. All patients underwent radio-anatomically guided radiofrequency ablation targeting anterior-right ganglionated plexi and right-inferior ganglionated plexi. Syncope and symptom burden, 24-hour ambulatory electrocardiogram data at presentation, and at follow-up were assessed along with procedural data. Results: A total of 23 patients underwent modified right-sided cardioneuroablation. Mean basal cycle length decreased significantly from 862.3 +/- 174.5 ms at the beginning of the procedure 695.8 +/- 152.1 ms following the final radiofrequency ablation (P <.001). Mean 24-hour ambulatory heart rate increased significantly from 66.4 +/- 10.7 bpm at baseline to 80 +/- 7.6 bpm at follow-up (P <.001). Only 1 patient had 1 episode of syncope following the procedure at the mean follow-up period of 10 +/- 2.9 months. The same patient had recurrent presyncope. Conclusion: The right-sided cardioneuroablation approach was found to be an effective treatment for vasovagal syncope and may be regarded as a default initial cardioneuroablation technique.