Research Information System
Kafkas Universitesi Veteriner Fakultesi Dergisi, vol.15, no.1, pp.95-101, 2009 (SCI-Expanded, Scopus, TRDizin)
In this study, it was aimed to investigate the effect of deslorelin, a GnRH analogue -which can postpone the sexual activity in some male animals-on the levels of plasma testosteron, testes size and side effects in Angora Bucks. As a animal material, 12 Angora male goat aged between 2-5 years and provided by Lalahan Animal Research Center. Animal were divided two equal groups. Deslorelin implants were replaced under the ear skin of goats (Group I, n=6) and left for 15 days. The animals of control group (Group II, n=6) had placebo treatment. After removal of implants, testicular size and epididiymal and plasma testosteron levels were determined. Plasma testosteron levels of deslorelin (4.08±1.9 ng/ml) estimated on 3rd day before implant removal was significantly higher than the those of control group (6.79±5.0 ng/ml) (P<0.05). Plasma testosteron levels estimated on day 6 th, (P<0.01), day 9th (P<0.05), day 12th (P<0.01), day 18th (P<0.05) and day 21st (P<0.05) after removal of implant were significantly different between the groups. The values of testicular volume, lenght, diameter, radius and epididiymal measurement were not significantly different (P>0.05) in groups. No side effects were seen during the deslorelin treatment, and sexual activity returned to normal after removing of implants, therefore it was suggetsed that deslorelin could be safely used as a succesful anti-fertility agent.