Primary adenosquamous carcinoma of the endometrium with glassy cell features. A diagnostic pitfall as a very rare tumour type in the endometrium

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SEVİM S., ENNELİ D., SERBES E. D., CANSIZ ERSÖZ C., YÜKSEL S.

PATHOLOGICA, vol.114, no.4, pp.332-338, 2022 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 114 Issue: 4
  • Publication Date: 2022
  • Doi Number: 10.32074/1591-951x-757
  • Journal Name: PATHOLOGICA
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.332-338
  • Keywords: adenosquamous, carcinoma, endometrium, glassy cell, pathology, CERVIX
  • Ankara University Affiliated: Yes

Abstract

Primary adenosquamous carcinoma of the endometrium with glassy cell features (ASC-GCF) is an extremely rare entity and to date, 16 cases of this entity have been reported in the literature. ASC-GCF is an aggressive histological subtype of cervical carcinoma with rapid growth and early metastases; however, very little is known about those originating from the endometrium as they are limited to only a few case reports. Herein, we report a case of primary adenosquamous carcinoma of the endometrium with extensive glassy cell features which posed a major diagnostic challenge by mimicking many entities with its histological diversity.