Evaluation of different phenotypic features and progression of Stargardt-fundus flavimaculatus disease with fundus autofluorescence imaging


BİNGÖL KIZILTUNÇ P., ŞERMET F., DEMİREL S., ÖZMERT E.

Retina-Vitreus, cilt.24, sa.4, ss.289-292, 2016 (Scopus) identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 24 Sayı: 4
  • Basım Tarihi: 2016
  • Dergi Adı: Retina-Vitreus
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.289-292
  • Anahtar Kelimeler: Fundus autofluorescence imaging, Fundus flavimaculatus disease, Stargardt disease
  • Ankara Üniversitesi Adresli: Evet

Özet

© 2016 Gazi Eye Foundation. All rights reserved.Purpose: To describe the clinical findings and disease progression of Stargardt-fundus flavimaculatus disease with fundus autofluorescence imaging and to evaluate their correlation with visual acuity. Materials and Methods: The visual acuity, fundus examination and fundus autofluorescence findings of patients were noted. Results: Patients with stage 1 showed increased autofluorescence with peripapillary sparing. At stage 2, there were flecks located in the extrafoveal region to the periphery. The active flecks were hyperautofluorescent, and the inactive flecks were hypoautofluorescent. At stage 3, the flecks were accompanied by macular atrophy. Atrophy progression was seen in 6 eyes. The number of flecks were increased in 8 eyes, and the hyperautofluorescent flecks became hypoautofluorescent in 6 eyes. There was no correlation between the stages of the disease and the visual acuity. Conclusions: The different phenotypic features determined by the FAF imaging in Stargardt-fundus flavimaculatus disease can give information about the progression and prognosis of the disease.