Akademik Veri Yönetim Sistemi
Asian Journal of Ophthalmology, cilt.9, sa.3, ss.122-124, 2007 (Scopus)
Aim: To investigate the eyelid and conjunctival bacterial flora and antibiotic resistance patterns of ocular signs of acne rosacea. Methods: Eighty randomly selected patients with acne rosacea underwent routine ophthalmic examination for ocular signs of rosacea. Samples from the eyelid and conjunctiva were obtained from all patients with acne rosacea with ocular signs and cultured aerobically. Bacterial isolates were identified and tested for antibiotic susceptibility. Results: Fifty patients (62.5%) had ocular involvement, of whom 31 (62.0%) had coagulase-negative Staphylococcus, 8 (16.0%) had no growth, 8 (16.0%) had Staphylococcus aureus, and 3 (6.0%) had Streptococcus pneumoniae. Of the coagulase-negative Staphylococcus, 12.9% showed nodrug resistance. Among the drug-resistant coagulase-negative Staphylococcus, 77.7% were resistant to bacitracin, 66.6% were resistant to polymyxin, 7.4% were resistant to tobramycin and gentamicin, and 14.8% were resistant to chloramphenicol, ofloxacin, ciprofloxacin, or norfloxacin; 59.2% were multi-drug resistant. Among S aureus, and 62.5% were resistant to bacitracin, 100% were resistant to polymyxin, and 12.5% were resistant to gentamicin and tobramycin; and 62.5% were multi-drug resistant. Among S pneumoniae, 100% were resistant to polymyxin. Conclusions: Coagulase-negative Staphylococcus was the most commonly isolated bacterium followed by S aureus. The high rate of bacitracin resistance and multi-drug resistance of coagulase-negative Staphylococcus and S aureus might adversely affect treatment of ocular rosacea. © 2007 Scientific Communications International Limited.