The incidence of β-thalassemia and abnormal hemoglobins in turkey


Çavdar A. O., Arcasoy A.

Acta Haematologica, vol.45, no.5, pp.312-318, 1971 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 5
  • Publication Date: 1971
  • Doi Number: 10.1159/000208641
  • Journal Name: Acta Haematologica
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, EMBASE, MEDLINE
  • Page Numbers: pp.312-318
  • Keywords: Abnormal haemoglobins, Haemoglobin A<inf>2</inf>, Thalassemia Turkey
  • Ankara University Affiliated: Yes

Abstract

The present study has been carried out to estimate the gene frequency of thalassemia and abnormal hemoglobins in a random Turkish population. A total of 1,000 blood samples have been studied. Fifteen of 900 adults had elevated Hb A2 concentrations. 0.60% of the population studied had an electrophoretically demonstrable hemoglobin abnormality: 3 Hb AS, 1 Hb AE, 1 Hb AD and one Hb A’2 (‘split’ A2). Signs of α-thalassemia were found in one case. This study indicates that the incidence of β-thalassemia trait in Turkish population as 1.66%. © 1971 S. Karger AG, Basel.