A very rare cause of virilization in childhood: Ovarian Leydig cell tumor

Arhan E., Cetinkaya E., AYCAN Z., ASLAN A. T., Yucel H., Vidinlisa S.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.21, sa.2, ss.181-183, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 2
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1515/jpem.2008.21.2.181
  • Dergi Adı: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.181-183
  • Anahtar Kelimeler: ovary, Leydig cell, rare, tumor, STROMAL TUMORS
  • Ankara Üniversitesi Adresli: Hayır

Özet

Virilization in childhood results from an adrenal and/or ovarian disorder. These children usually present with hyperandrogenism: acne, deepening voice, abnormal hair growth, cliteromegaly. Ovarian Leydig cell tumor is a very rare cause of hyperandrogenism in childhood. They are usually benign and surgical treatment is usually curative if the tumor is limited to the ovaries. We present the youngest case of ovarian Leydig cell tumor reported in the literature who presented with hyperandrogenism that was satisfactorily resolved after resective surgery. Rare causes of virilization should be investigated with special attention paid to tumoral disease in the differential diagnosis.