Multi response optimisation of polyphenol extraction conditions from grape seeds by using ultrasound assisted extraction (UAE)

VURAL N., Cavuldak O. A., Anli R. E.

SEPARATION SCIENCE AND TECHNOLOGY, vol.53, no.10, pp.1540-1551, 2018 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 10
  • Publication Date: 2018
  • Doi Number: 10.1080/01496395.2018.1442864
  • Journal Name: SEPARATION SCIENCE AND TECHNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1540-1551
  • Keywords: Grape seed, ultrasound-assisted extraction (UAE), response surface methodology (RSM), multi response optimisation, antioxidant activity, VITIS-VINIFERA L., PERFORMANCE LIQUID-CHROMATOGRAPHY, BOX-BEHNKEN DESIGN, PHENOLIC-COMPOUNDS, SURFACE METHODOLOGY, BIOACTIVE COMPOUNDS, BY-PRODUCTS, ANTIOXIDANT CAPACITY, GREEN EXTRACTION, NATURAL-PRODUCTS
  • Ankara University Affiliated: Yes

Abstract

Multi response optimisation conditions were investigated in grape seeds' phenolic compounds extraction by using ultrasound-assisted extraction (UAE) methodology. The effect of independent process variables such as EtOH concentration (0-100%), extraction time (0-40min), solvent:solid ratio (4.5-38.5mL/g) and extraction temperature (20-60 degrees C) on total phenolic content (TPC) and total antioxidant activity (TAA) of the extracts were studied. The optimum conditions of UAE were determined as follows: EtOH concentration, 61.76%; extraction time 20min., solvent:solid ratio, 30mL/g; extraction temperature 50 degrees C. The estimation results of the model and the experimental results for TPC and TAA showed a great similarity.