Akademik Veri Yönetim Sistemi
PAKISTAN VETERINARY JOURNAL, cilt.00, sa.00, 2023 (SCI-Expanded)
This study aims to determinate in vitro anthelmintic activity of the plant extracts
from the aerial part of five different Artemisia L. species (A. absinthium L., A.
abrotanum L., A. annua L., A. incana (L.) Druce, A. tournefortiana Rchb.) growing
in Türkiye. Depending on the ethnobotanical usage, the aqueous plant extracts were
prepared by decoction and maceration methods. The anthelmintic activity of the
plant extracts on Haemonchus (H.) contortus eggs and larvae was assessed using in
vitro test methods. The extracts were prepared in five concentrations (50; 25; 12.5;
6,25; 3.125 and 1.5625 mg/mL) by using PBS for egg hatch and larval motility
inhibition assay. In comparison to the negative control group, the extracts had
significant anthelmintic effect on H. contortus eggs and larvae (p<0.05). In the egg
hatch assay, all plants were found to be fully effective in the concentration range
studied. In the analysis of larval motility, the activity was correlated with the
quantities of the plant extracts. When the concentration-activity values of the plants
were examined for both extraction methods, the highest activity was in A. annua
and the lowest activity was observed in A. tournefortiana. Due to the development
of resistance to anthelmintic drugs, natural sources such as Artemisia species can be
considered as an alternative for the treatment of nematodes.