Central nervous system toxicity of cyclosporin A treatment in rheumatoid arthritis


Kutlay Ş., Savas S., Yalcin P., ATAMAN Ş., Ergin S.

BRITISH JOURNAL OF RHEUMATOLOGY, cilt.36, sa.3, ss.397-399, 1997 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 3
  • Basım Tarihi: 1997
  • Dergi Adı: BRITISH JOURNAL OF RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.397-399
  • Anahtar Kelimeler: rheumatoid arthritis, cyclosporin A, neurotoxicity, A TOXICITY, TRANSPLANTATION
  • Ankara Üniversitesi Adresli: Evet

Özet

A 35-yr-old woman with rheumatoid arthritis, receiving cyclosporin A, presented with diplopia, ptosis, loss of horizontal and vertical eye movements, dysarthria, nasal regurgitation. After differential diagnosis, cyclosporin A neurotoxicity was suspected and the treatment stopped. All side-effects were reversed with the discontinuation of the drug. Central nervous system neurotoxicity with low-dose cyclosporin A treatment was discussed.