Non-persistent pesticides in breast milk in an agricultural area in Turkey

Yildizdas H. Y., GÜLDEREN ÖZLÜ F., Efeoglu P., DAĞLIOĞLU N., SATAR M.

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, cilt.32, sa.14, ss.2387-2392, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 14
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1080/14767058.2018.1438395
  • Dergi Adı: JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2387-2392
  • Anahtar Kelimeler: Breast milk, estimated daily intake, non-persistent pesticides, PRENATAL EXPOSURE, FETAL EXPOSURE, ORGANOCHLORINE, MECONIUM, CONTAMINANTS, EXTRACTION, GROWTH, WOMEN, ASSOCIATION, METABOLITES
  • Ankara Üniversitesi Adresli: Hayır

Özet

Background: Organophosphates, pythyreoids, carbamate pesticides and fungicides are heavily used in agriculture. They may have dangerous effects on newborn health especially on immune system and growth via prenatal transmission by placenta or postnatal transmission by breastfeeding. Methods: In 2015, 144 non-persistent pesticides in 64 milk samples of 32 mothers were studied by OuEChERS method in liquid chromatography/tandem mass spectrometer in neonatal Intensive Care Unit in Adana, a city in Cukurova region which is an important agricultural area in Turkey. Results: Pesticides were detected in milk samples of 11 mothers (34.3%) and 21 (32.8%) of milk samples. In five mothers, fungicides (in 5/10 samples propicanozole-PP, in 4/10 samples bromucanozole-BM), in five mothers, organophosphates (in 10/10 samples primyphosphomethyl-PPM), in one mother, both organophosphates and fungicide (in 1/2 samples PPM and in 1/2 samples buprimate) were detected. However, the estimated daily intakes (EDI) were less than acceptable daily intakes (ADI) for PPM, PP and BM, respectively. Conclusions: Although pesticides levels in human milk did not exceed the ADIs, we suggest monitoring pesticides in human breast milk especially for newborn health.